A premium sachet-based senolytic protocol formulated with Fisetin, Quercetin, and Piper Longum to support healthy aging, cellular renewal, and inflammatory balance.


Each sachet contains one daily serving of three capsules. The sachet format supports consistent dosing, compliance, travel convenience, and professional presentation for distributors, clinics, and healthcare practitioners.
Designed to support the body’s natural processes associated with cellular renewal and healthy aging.
Formulated with ingredients studied for roles in oxidative stress, inflammation, and cellular aging pathways.
Part of TWIG’s protocol-based longevity platform for structured monthly use.
Take 1 sachet daily for 5 consecutive days once per month, or as directed by your healthcare provider.
Some research suggests that during these “senolytic days,” it may be best to avoid high doses of additional antioxidants or polyphenols, as these could potentially counteract the cellular stress signals that fisetin and quercetin rely on for their activity.
Each box provides enough sachets for a complete 3-month program.

Serving Size: 1 Sachet (3 capsules)
| Fisetin | 500 mg † |
| Quercetin | 750 mg † |
| Piper Longum | 20 mg † |
† Daily Value not established
Other Ingredients: Microcrystalline cellulose, silica, vegetable capsules.

TWIG Senolytics is manufactured in Ontario, California, USA, with commercial operations based in Miami Beach, Florida.

Fisetin is a naturally occurring flavonoid studied for its relationship to senescence, cellular aging and senolytic pathways.
Quercetin has been studied for roles related to oxidative stress, inflammation and cellular aging.
Piper Longum is included to support absorption and enhance the effectiveness of the protocol design.

Discover the future of longevity with therapies that harness cutting-edge science and AI to promote cellular renewal, elevate vitality, and support youthful energy.
Most supplement formulas combine many ingredients without considering how they may interact — and in some cases, ingredients may counteract the effects of others. At TWIG, products are built on protocol-driven design, precision dosing, and targeted cellular pathways.
Each protocol is developed with a clear purpose, ensuring that every ingredient contributes to its intended effect with transparency, simplicity, and measurable quality.